Metabolic Syndrome
Metabolic syndrome is a cluster of the most dangerous heart attack risk factors: diabetes and raised fasting plasma glucose
Database
This database aims to collect the manually curated associations between metabolic syndrome and non-coding RNA (microRNA, lncRNA and circRNA). In the current release, this database provides 1505 associations between 1289 miRNAs, 200 lncRNAs and 16 circRNAs and metabolic syndrome and its characteristic diseases (abdominal obesity, type 2 diabetes mellitus, hypertension, hypertriglyceridemia and reduced high-density lipoprotein cholesterol) across 6 species from more than 4000 published articles.
Metabolic Syndrome
Metabolic Syndrome is a group of clinical symptoms that are characterized by obesity (especially abdominal obesity), hyperglycemia (diabetes or impaired glucose regulation), dyslipidemia (hypertriglyceridemia and reduced high-density lipoprotein cholesterol) and hypertension.
microRNA
microRNA is a class of non-coding single-stranded RNA molecules about 22 nucleotides (nt) in length, which is involved in post-transcriptional gene expression regulation in plants and animals. A large amount of evidence suggests that microRNAs play critical roles in a number of human diseases, including metabolic diseases.
lncRNA
lncRNA is a novel class of long noncoding RNA molecules larger than 200 nucleotides (nt), which regulates a variety of biological processes by a diverse interplay of mechanisms including recruitment of epigenetic modifiers, transcriptional and post-transcriptional regulation, control of mRNA decay, and sequestration of transcription factors.
circRNA
circRNA is a new class of non-coding RNA molecules that is different from traditional linear RNA, which has a closed circular structure and is abundantly present in the eukaryotic transcriptome. Most circRNAs are composed of exome sequences, which are conserved in different species, and have expression specificities for tissues and different developmental stages.
